Lymphoma Cancer

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Introduction

Lymphoma cancer is the cancer that forms in the lymphatic system. The lymphatic system fights off germs in your body. There are 2 main types, which include: Hodgkin's lymphona and non-hodgkin's lymphona. The main places where cancers form are lymphnodes, lymph vessels, spleen, bone marrow, thymus, adenoids and tonsils, and the digestive tract. The most common type of hodgkin lymphoma is known as Classic Hodgkin lymphoma with the less common being Nodular lymphocyte-predominant Hodgkin lymphoma. With non-Hodgkin lymphoma, there are B lymphocytes and T lymphocytes. The Hodgkin Lymphoma risk factors can be seen here and the non-Hodgkin lymphoma risk factors can be seen here.

Mechanisms and genetic alterations

The most common mutated genes for non-Hodgkin lymphoma are KMT2D, MYD88, PIM1, CREBBP, BCL2, SPEN, ARID1A.

Current lymphoma cancer treatments

For Hodgkin lymphoma

New treatments in clinical trials