Pancreatic Cancer

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Types of Pancreatic Cancer

Introduction

Pancreatic cancer forms from the pancreas. The most common type known is known as pancreatic adenocarcinoma, and the less common being pancreatic neuroendocrine tumors. ~95% of pancreatic cancers are adenocarcinomas, which mostly happen in the pancrease's ducts. Pancreatic cancer often happens due to exocrine cells in the pancreas grow wildly. Many factors including what someone does and their genetics contribute to getting pancreatic cancer (more information)

Mechanisms and genetic alterations

The most common mutated genes include KRAS, TP53, SMAD4, CDKN2A, CDKN2A, ARID1A, LRP1B

Current pancreatic cancer treatments

When the pancreatic cancer hasn't spread far past the pancrease surgery can be used. After surgery, chemo/radiation therapy is used. If the tumor is too large, a chemo/radiation therapy treatment is used to make the tumor smaller. If the pancreatic cancer got to blood vessels but haven't grown too much in them, then chemo/radiation therapy combined with surgery is used. If the cancer has grown too far then chemotherapy is used. Drugs such as Gemcitabine or FOLFIRINOX are used (more information).

New treatments in clinical trials